Bruce covered the song only once:
1988-06-25 - WEMBLEY STADIUM, LONDON, ENGLAND
During a rehearsal take that also featured Patti Scialfa on harmony vocals. The recording, which is in circulation among collectors, appears to be taken from a line feed and is believed to be from a 1988 sound-check but the exact date and venue are unknown. Bruce Springsteen sound-checked the song in 1988 during the Tunnel Of Love Express Tour but he never performed it on the tour's or any other tour's regular shows. At least one sound-check date has been confirmed: 25 Jun 1988 at Wembley Stadium in London, England. An eyewitness recounted: "'Gulf Coast Highway' was played at the sound-check of the Wembley Stadium gig on the TOL tour in 1988. I was outside waiting to get in and it sounded wonderful, I was a little disappointed they didn't play it on the night."
Bruce Springsteen recorded ' Gulf Coast Highway ' also in studio in 1989 as a duet with then-girlfriend Patti Scialfa. Rob Tannenbaum wrote in the 11 Jan 1990 issue of Rolling Stone: "Since the Amnesty tour ended in October 1988, Springsteen has been on a sabbatical from touring and recording. He has spent much of that time in Los Angeles, where he is rumored to be producing a solo album for girlfriend Patti Scialfa. Two tracks are known to have been recorded by Scialfa: a version of Nanci Griffith's 'Gulf Coast Highway' ." In concerts, Nanci Griffith referenced singers who have recorded Gulf Coast Highway as a duet. The list included some officially released versions, including Dave Mathews and Emmy Lou Harris
, but she also mentioned Bruce Springsteen and Patti Scialfa. For example, introducing the song on 26 May 1989 in Dallas, TX, she said: "This next song is a tune that Bruce Springsteen and Patti Scialfa just recorded, and it's a song that they're doing as a duet."